We carry out deep brain recordings by leveraging intracranial clinical interventions. Patients receive surgery for the treat mentor diagnosis of brain disorders, opening a unique opportunity to study brain activity in a way that would otherwise not be possible.
In addition to recording brain activity, we utilize targeted electrical stimulation. This provides causal evidence for the involvement of individual brain areas in behavior, and can also be used for therapeutic interventions.
Using custom-made carbon fiber electrodes, we measure the concentration of neuromodulators intimately involved with cognition and disease such as dopamine and serotonin with high temporal (sub-second) resolution and anatomical accuracy.
To understand how decisions are made, we need to observe behavior. Using quantifiable and reproducible tasks (i.e.computer games) inspired by behavioral economics and game theory, we can elucidate how humans make decisions.
We analyze behavior through a computational modeling lens. This allows us to categorize and quantify individual behavior and examine the underlying factors of decision making.
To examine brain function, we record electrical activity during behavioral tasks. This electrophysiological response provides a rich characterization of neuronal activity and brain oscillations with high temporal resolution in the context of behavior.
